Pharmacological action of nitrovasodilators
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- Mechanism of action Nitrovasodilators are prodrugs that donate NO by various mechanisms. ... NO stimulates the soluble form of the enzyme guanylate cyclase in the smooth muscle cells of blood vessels. Guanylate cyclase produces cyclic guanosine monophosphate (cGMP) from guanosine triphosphate (GTP).
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