Question

physical properties of aminolysis reaction​

Answer 1

Answer:

Aminolysis of C4 and C2 chlorine substituents is readily used to obtain 4- or 2-aminoquinazolines, respectively. Similar to pyrimidines, a 4-chloro substituent reacts much faster than a 2-chloro, which enables regioselective amination. Quinazolinones are converted to 4-aminoquinazolines following activation via BOP and DBU.94,95

Explanation:

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