Physicixhemical and biological properties of drug molecules for predicting adme
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Drugs are chemical molecules that may be arranged and classified according to their medical use into the following: (a) drugs that act on the various physiological functions of the body, which can be grouped together as pharmacodynamic agents, for example sedatives, analgesics, antipyretic and antirheumatic agents, antipsychotic, antihistaminic and antiallergic drugs, anti-inflammatory agents, diuretics, cardiovascular agents and drugs acting on the heart, and adrenergic and cholinergic agents and drugs acting on the gastrointestinal tract (GIT), etc., (b) central nervous system (CNS) Agents, for example antidepressant drugs, anesthetic, hypnotic drugs, etc., (c) drugs that are used to fight pathogenic organisms can be grouped together as chemotherapeutic agents, for example sulfonamides, antibiotics, anti-infective agents, antimicrobial, antiamoebic, antifungal agents, antiviral agents, anticancer agents, antimalarial agents, etc., and (d) supplement agents, for example vitamins, dietary supplements, etc. [1],[2] .
In general, the chemical structure of any drug profoundly affects both its pharmacodynamic and pharmacokinetic properties, irrespective of the subclass that drug belongs to. In the following sections, we will discuss the impact of the structural features of the drugs on the pharmacological actions, illustrated with many examples from various drug families.
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hope this helps
Drugs are chemical molecules that may be arranged and classified according to their medical use into the following: (a) drugs that act on the various physiological functions of the body, which can be grouped together as pharmacodynamic agents, for example sedatives, analgesics, antipyretic and antirheumatic agents, antipsychotic, antihistaminic and antiallergic drugs, anti-inflammatory agents, diuretics, cardiovascular agents and drugs acting on the heart, and adrenergic and cholinergic agents and drugs acting on the gastrointestinal tract (GIT), etc., (b) central nervous system (CNS) Agents, for example antidepressant drugs, anesthetic, hypnotic drugs, etc., (c) drugs that are used to fight pathogenic organisms can be grouped together as chemotherapeutic agents, for example sulfonamides, antibiotics, anti-infective agents, antimicrobial, antiamoebic, antifungal agents, antiviral agents, anticancer agents, antimalarial agents, etc., and (d) supplement agents, for example vitamins, dietary supplements, etc. [1],[2] .
In general, the chemical structure of any drug profoundly affects both its pharmacodynamic and pharmacokinetic properties, irrespective of the subclass that drug belongs to. In the following sections, we will discuss the impact of the structural features of the drugs on the pharmacological actions, illustrated with many examples from various drug families.
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