Place the steps for the formation of the enzyme pepsinogen in the correct order.
1. The DNA strands unwind, and
RNA polymerase binds to the
template strand.
2. The mRNA undergoes intron
splicing and exits the
nucleus.
3. The tRNA moves through mRNA
with the activated amino acids
attached to it.
4. The synthesis of mRNA begins.
The amino acids assemble
to form peptide.
Answers
the levers in the passage are:
- sea-saw
-wheelbarrow
-squeezer
-tongs
There are two factors that involve the ability of enzymes to process RNA.
1) Structure see wikipedia
2) Binding affinitya
Let's take a look at the splicing process: enter image description here
The active 'sites' (GU,A & AG) need to be in spatial proximity (point one), and the enzyme needs to be able to bind there, aka forming hydrogen bonds with the nucleotides, which is mostly the case if:
a) the nucleotides are 'free' as in they are not paired with other nucleotides
b) it is energetically favorable for the enzyme to bind and do its work, which factors like temperature, and of course on the correct nucleotides
If there were some mutations, the splicing might not work.
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