Plasmodium species are pathogenic. Particular genes present in their DNA might be responsible for that. If that particular gene(s) is/are removed, will that become non pathogenic and harmless? And if that plasmodium is allowed to multiply, will we able to produce harmless and non pathogenic plasmodium? Is there possibility for my idea?
Answers
Answer:
if u culture a group of plasmodium which are non pathogenic (you said a particular gene is removed which is responsible for pathogenic nature of that organism) then that culture "maybe" be non pathogenic to us
but if u look at Martha chase and Harshey's experiment on E.coli and a bacteriophage they did that experiment to prove the world that DNA is the genetic material and it transfers to its progeny.
And here plasmodium being a sporozoan
it performs sexual reproduction in musquito as we know that in sexual reproduction variations occurs.
coming to ur culture there might not be plasmodium species which are pathogenic but in this world how can you search for each and every plasmodium to be changed into non pathogenic forms. okay if u transform as much as 99% of plasmodium into non pathogenic form and there is a chance that when u r conducting this there may be an infectious plasmodium in the gut of mosquito and performing it's sexual reproduction, that one plasmodium again infects the man. there is a possibility.
so there is 0 probability to ur idea sry to say this. but it takes some decades to eradicate the species of plasmodium completely if humanity works on it perfectly