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1. It is not recirculated because the kidneys does not have the capability to filter the dialysate.
2.The blood flows in one direction and the dialysate flows in the opposite. The counter-current flow of the blood and dialysate maximizes the concentration gradient of solutes between the blood and dialysate, which helps to remove more urea and creatinine from the blood.
3.The maintenance of constant osmotic pressure in the fluids of an organism by the control of water and salt concentrations.
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