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16. Nitrogenous bases are split into two different types: the purines (adenine and guanine) and the pyrimidines (thymine, cytosine, and uracil). A purine will hydrogen-bond to a pyrimidine. Adenine always bonds with thymine (in DNA ) or with uracil (in RNA ) with two hydrogen bonds.
The purines in DNA are adenine and guanine, the same as in RNA. The pyrimidines in DNA are cytosine and thymine; in RNA, they are cytosine and uracil. Purines are larger than pyrimidines because they have a two-ring structure while pyrimidines only have a single ring.
17. A nucleotide consists of a sugar molecule (either ribose in RNA or deoxyribose in DNA) attached to a phosphate group and a nitrogen-containing base. The bases used in DNA are adenine (A), cytosine (C), guanine (G), and thymine (T). In RNA, the base uracil (U) takes the place of thymine.
18. The bond joining two successive nucleotides in the same strand of DNA is called the phosphodiester bond. Strong covalent bonds form between the phosphate group and two 5-carbon ring carbohydrates (pentoses) over two ester bonds.
A phosphodiester bond occurs when two of the hydroxyl groups in phosphoric acid react with hydroxyl groups on other molecules to form two ester bonds.
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