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Answers
Answer:
2.Saperation of Blood Plasma from blood
Explanation:
Centrifugation is considered to be the gold standard for plasma separation. It uses the difference in density to separate the plasma from the cells. The artificial gravity generated by rotation enables fast sedimentation of RBCs that are either filtered out or concentrated at the bottom of a vessel prior to manual extraction of the supernatant plasma. The same artificial gravity is employed in centrifugal microfluidics as realized for nucleic acid analyses, immunoassays, and cell analyses
Thus, the implementation of blood plasma separation in centrifugal microfluidics is straight forward. Yet, transfer of purified plasma into spatially separated reaction vessels has often been omitted . A major challenge for such a spatial separation of RBCs and plasma is the robust valving of plasma while preventing carryover of RBCs. Sedimentation alone can be used for applications that do not require highly purified plasma and/or include read-out at continuously high rotational frequencies so that cell resuspension is suppressed. Automated blood plasma separation with spatial separation of blood cells and plasma into separate reaction vessels, however, asks for more complex solutions.
