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In prokaryotes, the DNA (chromosome) is in contact with the cellular cytoplasm and is not in a housed membrane-bound nucleus. In eukaryotes, however, the DNA takes the form of compact chromosomes separated from the rest of the cell by a nuclear membrane (also called a nuclear envelope).
So the answer is nuclear envelope.
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In some organisms like bacteria, the nuclear region of the cell is poorly defined due to the absence of a nuclear membrane. Such organism with cells, lacking a nuclear membrane, are called prokaryotes.
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