Question

Pr55 alpha, a regulatory subunit of pp2a, specifically regulates pp2a-mediated beta-catenin dephosphorylation

Answer 1

PR55 alpha, a regulatory subunit of PP2A, specifically regulates PP2A-mediated beta-catenin dephosphorylation. ... A central question in Wnt signaling is the regulation of beta-catenin phosphorylation and degradation. Multiple kinases, including CKI alpha and GSK3, are involved in beta-catenin phosphorylation.