Question

preparation of aspirin from benzene​

Answer 1

Explanation:

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HOOC-CH-OH + ( CHCOCl + NaOH) →HOOC-CH-O-CO-CH + HCl. In this way, aspirin can be obtained from benzene.

Answer 2

There are multiple ways to do this, but I will explain it via some easy to understand, so called "standard" reactions.

First, benzene is chlorinated using a Cl2/AlCl3 or Cl2/FeCl3 mixture to form chlorobenzene. This is a standard electrophilic aromatic substitution reaction.

Next, heat chlorobenzene with NaOH at sufficiently high temperature(about 350°C) to obtain phenol.

Then treat phenol with CHCl3/KOH mixture, to obtain o-salicylic acid via the well known Reimer-Tiemann Reaction.

Finally, salicylic acid is treated with acetic anhydride (Ac2O), to give o-acetyl salicylic acid, also commonly known as aspirin.

Hope this helps!