production of hirudin from transgenic brassica napus deeds_??
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production of hirudin from transgenic brassica napus deeds_??
Hirudin is a naturally occurring, anticoagulant produced and secreted in the sallvary glands of the medicinal leech, Hirudo medicinalis, with a number of desirable properties. Hirudin has been made in variety of microorganisms including yeast and E. coli but these entail significant costs associated with fermentation
Therefore, the gene-encoding hirudin was chemically synthesized and introduced into Brassica napus using Agrobacterium-mediated transformation. The resulting transgenic plant yielded seeds in which hirudin accumulates. The hirudin is purified and used as medicine. In this case, the transgenic product itself is the product of interest.
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