Protein structure determination by c and n terminal residue determination
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Protein Isolation and Determination of Amino Acid Sequence The C-terminal residue is determined by the use of either a chemical reagent or the enzyme carboxypeptidase.Carboxypeptidase is an exopeptidase that specifically hydrolyzes the C-terminal peptide bond and releases the C-terminal amino acid.
In biochemistry and molecular biology, a residue refers to a specific monomer within the polymeric chain of a polysaccharide, protein or nucleic acid. One might say, "This protein consists of 118 amino acid residues" or "The histidine residue is considered to be basic because it contains an imidazole ring."
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