Protein with a prosthetic group
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When bound to proteins, prosthetic groups are called holoproteins. Some examples of prosthetic groups are heme, biotin, flavin, iron sulfides, copper and ubiquinone.
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Prosthetic group: They are organic compounds and are tightly bound to the apoenzyme. For
example, haem is the prosthetic group in peroxidase and catalase enzymes that catalyse the
breakdown of hydrogen peroxide to water and oxygen. Haem (prosthetic group) is a part of the
active site of the enzyme.
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