Question

Q. 1 Calculate the catalytic activity of pyruvate kinase ? ​

Answer 1

Explanation:

Pyruvate kinase is the enzyme involved in the last step of glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to adenosine diphosphate (ADP), yielding one molecule of pyruvate and one molecule of ATP. Pyruvate kinase was inappropriately named (inconsistently with a conventional kinase) before it was recognized that it did not directly catalyze phosphorylation of pyruvate, which does not occur under physiological conditions.Pyruvate kinase is present in four distinct, tissue-specific isozymes in animals, each consisting of particular kinetic properties necessary to accommodate the variations in metabolic requirements of diverse tissues.

Answer 2

Explanation:

Pyruvate kinase is the enzyme involved in the last step of glycolysis. It catalyzes ... Pyruvate kinase activity is most broadly regulated by allosteric effectors, covalent modifiers