Q.1 Three given polypeptides (P. Q and R ), of same size and same pl (7.2), have a single aspartic acid in each of them. In polypeptide P. the aspartic acid residue is on the surface. In polypeptide Q, it is surrounded by negatively charged residues, whereas in polypeptide R it is deeply buried in a hydrophobic core. pka of the side chain carboxylate of free (in solution) aspartic acid is 3.65. The polypeptides are in a buffer of pH 7.4. The change in pKa of the aspartic acid side chain carboxylate in the polypeptides P, Q and R is likely to 1 remain the same in P, modest increase in Q and greater increase in R Ans X 2. remain the same in all the three polypeptides X3 increase in P, decrease in Q and remain the same in R X remain the same in P, increase Q and decrease in R is likely to.
Answers
Answered by
0
Explanation:
by H Lodish · 2000 · Cited by 51 — The spatial organization of proteins, their shape in three dimensions, is a key to ... All 20 different amino acids have this same general structure, ...
Similar questions