Question

Q.124 splitting of centromeres and separation of chromatids occurs at

Answer 1

Anaphase is stage of mitosis after the metaphase when replicated chromosomes are split and the daughter chromatids are moved to apposite poles of the cell in a fine manner.

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Centromeres separate and  also chromatids of each chromosome to move to opposite on the spindle.

Answer 2

Explanation:

During anaphase the centromere attaching two sister chromatids splits and the sister chromatids are pulled towards poles by shortening of spindle fibres.