Q.154. Select a set of items which are responsible for blood coagulation.
1) Mast cells, Ca2+, Erythrocytes
2) Fibrin, Fe2+, elastin
3) Thrombocytes, vitamin k, Fe2+
4) Fibrin, vitamin k, Ca2+
Answers
4. Fibrin, Vitamin K, Ca²+.
[Acc. to NCERT]
• Coagulation of blood : When an injury happens the blood platelets basically disintegrate and release a type of phospholipid called
platelet factor-3 (platelet thromboplastin). The injured tissues also release a lipoprotein factor called thromboplastin these two factors combined with calcium and certain proteins of the blood plasma to form an enzyme called prothrombinase. Prothrombinase catalyzes breakdown of prothrombin into an active enzyme called thrombin and some small peptide fragments. Thrombin brings about depolymerization of fibrinogen into its monomers. Later thrombin stimulates repolymerization of these monomers into long insoluble fibre-like polymers called fibrin. The thin, long and solid fibres of fibrin form a clot which seals the wound and stops bleeding.