Q.23 Describe various types of granulocytes.
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The specific types of granulocytes are neutrophils, eosinophils, and basophils
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1. Basophils are white blood cells that fight infection.
- It is the least prevalent form of granulocyte, accounting for just around 0.5 percent of circulating blood leukocytes.
- It serves a variety of functions, including CD4+ cell activation and differentiation, antigen presentation, and so on.
- Their nucleus is lobed, with two lobes connected by thin chromatin filaments.
Eosinophils are a kind of white blood cell that produces a substance called
- Nearly 1% of all circulating leukocytes are from this group. In immunological responses and the pathophysiology of autoimmune and allergy disorders, these structures play a variety of roles.
- Due to their proclivity to degranulate in the circulation, their granule count might fluctuate.
- Their nucleus is lobed and has a kidney shape.
- Their granules contain a one-of-a-kind protein that is essential for parasite elimination.
Neutrophils, number three.
- These are the most common leukocytes in humans' bodies, despite the fact that there are many additional varieties.
- It serves as the body's first line of defence against infection.
- These phagocytes make up 60-65 percent of all circulating white blood cells and can be found throughout the body.
- Neutrophil-killers and neutrophil-cagers are the two components of these cells.
- Neutrophils leave the circulation to travel to the infection location after getting appropriate signals.
Mast cells, number four.
- These granulocytes can be detected in tissues with a lot of histamine and heparin in the granules.
- Their involvement is critical in immunological tolerance, allergies, and pathogen response (parasites, for example).
- They regulate and modulate neuroimmune system responses as well as mediate autoimmunity and inflammation.
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