Q. Blood is drawn from a child with severe anemia and the haemoglobin protein is degraded for peptide and amino acid analysis. Of the results below, which change in hemoglobin primary structure is most likely to correlate with the clinical phenotype of anemia?
a. ile-leu-val to ile-ile-val
b. leu-glu-ile to leu-val-ile:
c. gly-ile-gly to gly-val-gly.
d. gly-asp-gly to gly-glu-gly
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C.gly-Ike-gly to gly-val-guy
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