Q.The size of particles in a parenteral suspension should be
A. 10 to 20 um B Less than 10 pm C 100 to 200 um D.50 to 100 pm
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The correct option is B Less than 10 pm
Explanation:
- Suspension particle size is important for medication release and stability in oral and parenteral formulations.
- However, the effect of particle size in suspension formulations on tissue injury (myotoxicity) after intramuscular (IM) injection has not been well studied.
- Parenteral suspensions are dose formulations that contain medicines that are poorly soluble in water.
- Drugs in suspension form improve drug solubility and stability. Sulfonated drugs have enormous surface areas.
- When compared to solution, parenteral suspensions give a faster start of action and a longer line on time.
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