Question

+ QNo.34 Which of the following
electrophilic substitution reaction is
not possible in pyridine?
A. Nitration
B. Sulphonation
C. Bromination
D. Friedel craft reaction​

Answer 1

Answer:

Common alkylations and acylations, such as Friedel–Crafts alkylation or acylation, usually fail for pyridine because they lead only to the addition at the nitrogen atom.

Answer 2

Option D). Friedel craft reaction​

Friedel craft reaction​ electrophilic substitution reaction is not possible in pyridine.

• When substituents are attached to aromatic rings, Friedel-Crafts reactions, which involve an electrophilic aromatic substitution, are utilized to do so. Alkylation and acylation reactions are the two main categories of Friedel-Crafts processes.
• The Lewis acid and the chlorine atom of the acid chloride form a complex during the Friedel-Crafts acylation reaction. Cleaving the complex's C-Cl link produces an acylium ion. The acylium ion is resonance stabilized and has a positive charge on the carbon atom.
• The formation of C-C bonds and the activation of C-H are two of organic chemistry's most crucial applications of Friedel-Crafts reactions. Friedel-Crafts style alkylations serve as the building blocks for the creation of a wide range of industrial goods by attaching an alkyl group to an arene molecule.
• The process is called a Friedel-Crafts reaction, and aluminium trichloride is the catalyst. Instantaneous polymerization occurs. The liquid medium and rubber particle suspension are put into the boiling water. Unreacted monomers and methyl chloride are collected and stored.

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