Question 11:Which of the following is an unusual
feature of the replication cycle in coronaviruses:
1) The RNAs all terminate in a common 3 and pro
nested set transcripts
b) They take advantage of recombination with the tony
RNA genome
c) They are not highly mutable
d) They use capped cellular mRNA'S
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Answer:
Explanation:
Coronaviruses have large positive-strand RNA genomes that are 5′ ... cell structures and functions to complete their life cycle, and they also use ... constituting a 3′-coterminal nested set of RNAs (reviewed in). ... To date, possible roles of eIF4F in viral mRNA translation have not reported for other CoVs.
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An unusual feature of the replication cycle in corona-viruses is 1) The RNAs all terminate in a common 3 and produce nested set transcripts.
Explanation:
- In coronavirus, during replication, there are many processes are involved such as genome translation involves ribosome frameshifting, formation of genomic and multiple subgenomic RNAs and assembly of progeny virions in a unique pathway.
- RNA is a highly mutable compound in which recombination of compound occurs but not to high frequency.
- In coronavirus, there are 8 sub genomic mRNAs in which all RNAs terminate at the common 3´ end of the genome.
- But they start at various places from 5´ end to form a nested set of 3´co-terminal transcripts.
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