Question if the Day ----
© :- why regeneration is slow process in human beings??
Answers
Answer:
Regeneration in humans is the regrowth of lost tissues or organs in response to injury. This is in contrast to wound healing, or partial regeneration, which involves closing up the injury site with some gradation of scar tissue. Some tissues such as skin, the vas deferens, and large organs including the liver can regrow quite readily, while others have been thought to have little or no capacity for regeneration following an injury.
Numerous tissues and organs have been induced to regenerate. Bladders have been 3d printed in the lab since 1999. Skin tissue can be regenerated in vivo, and in vitro. Other organs and body parts that have been procured to regenerate include: penis, fats, vagina, brain tissue, thymus, and a scaled down human heart. Ongoing research, aims to induce full regeneration in more human organs.
Explanation:
PLEASE MARK AS A BRAINLIEST
Explanation:
sounds ridiculous, but there's a growing number of scientists that believe body part regeneration is not only possible, but achievable in humans. After all, not only are there plenty of animals that can do it, we can do it ourselves for our skin, nails, and bits of other organs.
What's more, we've got a lot of the genes for it. "I really think we as humans have the potential to regenerate, but something isn't allowing that to happen," says Billie Swalla, director of Friday Harbor Laboratories and and a Biology professor at the University of Washington, and part of a team that's closely studying regeneration in some of our invertebrate relatives. "I believe humans have these same genes, and if we can figure out how to turn on these genes, we can regenerate."
An intact, live acorn worm - the head is on the far left, and the worm will be cut in the middle
An intact, live acorn worm - the head is on the far left, and the worm will be cut in the middleShawn Luttrell/University of Washington
Swalla and research partner Shawn Luttrell, also from the University of Washington, have been looking at the acorn worm; a small aquatic worm that burrows in the sand around coral reefs.
Acorn worms are interesting for two reasons. Firstly, they have the ability to regenerate every part of their body, including the head, nervous system and internal organs. Cut one in half, and within 15 days each half will regenerate into a whole worm so perfectly you couldn't distinguish it from one that had never been cut.
But secondly, they're also remarkably similar to humans, both genetically and in terms of how their body structure is laid out. In fact, thanks to their ancestral relationship with chordates like ourselves, acorn worms have a lot of DNA in common with us.
A close-up view of the cut site and tail end of the worm the day it was cut
A close-up view of the cut site and tail end of the worm the day it was cutShawn Luttrell/University of Washington
"We share thousands of genes with these animals, and we have many, if not all, of the same genes they are using to regenerate their body structures," says Luttrell, "This could have implications for central nervous system regeneration in humans if we can figure out the mechanism the worms use to regenerate."
Through DNA, every cell in our bodies contains the roadmap to build or re-build the entire machine. But for some evolutionary reason, this process has been blocked off. Perhaps we're flat out too big for it to be worthwhile from an energy perspective, as opposed to smaller amphibians and fish. Maybe our immune systems spoil the party by building up scar tissue around cuts.
Thus, the researchers have been trying to figure out the gene expression patterns that happen when these Acorn worms are regenerating. They suspect there's some sort of "master control" gene that starts the process off, because once it begins, it follows the same steps in every worm.
Five days after being cut - a rudimentary head, including the mouth and proboscis, has formed
Five days after being cut - a rudimentary head, including the mouth and proboscis, has formedShawn Luttrell/University of Washington
They're also trying to work out exactly which types of cells the worms use as the building blocks of a regeneration – be they stem cells, or other cells that could be repurposed for regrowth.
The eventual goal is to learn how to activate the process in other animals, including humans, through gene editing or activation, and supply the necessary materials to let it work.
It's a complex problem, but genetically we're working from a strong starting point. And if it's possible to regenerate tissue the same way as an Acorn worm does, that will include the nervous system, heart and other internal organs. A pretty amazing process to think about, but could this be an accepted medical reality in 100 years?