Question. The Tonowmg pepude sequence was to win a rarger proten (ignore we
pKa of the amino and carboxy termini). ---W-V-R-K-E---- What is the net charge on this
peptide region at pH 6?
A)-1
B) 0
C) +1
D) +2
Question 7: The following peptide sequence was found within a larger protein (ignore the
pKa of the amino and carboxy termini). ---A-A-A-R-R-E-A-A---- Will the pKa of each
arginine be the same?
A) Yes, the pKa is a fixed constant.
B) No, the pKa is dependent on the pH of the solution
C) No, the local environment would impact the pKa of each R, due to electrostatic repulsion
D) Yes, because it is palindromic
Question 8: What is a protein domain?
a
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