radical cure of plasmodium vivax malaria is by
Answers
Answer:
The World Health Organization (WHO) guidelines for the radical cure of vivax malaria currently recommends the use of a daily dose of 0.25 mg/kg/day (3.5 mg/kg total dose) primaquine taken with food once daily, co-administered with chloroquine or artemisinin combination therapy (ACT) depending on chloroquine sensitivity ...
Answer:
The primary determinant of primaquine radical cure efficacy is the total dose of primaquine administered. In areas with frequent-relapsing strains of Plasmodium vivax, WHO recommends a high-dose primaquine regimen of 7 mg/kg administered over 14 days (0·5 mg/kg per day, equivalent to an adult dose of 30 mg per day).
Explanation:
Radical cure: (also: radical treatment) Complete elimination of malaria parasites from the body; the term applies specifically to elimination of dormant liver stage parasites (hypnozoites) found in Plasmodium vivax and P.