Reaction of acetyl chloride with ch2n2 and ag2o
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Answer:
The Arndt–Eistert reaction involves a series of chemical reactions that synthesise a carboxylic acid from its homologue with one fewer carbon atoms (i.e. the conversion of RCOOH to RCH
2COOH).[1][2][3] Named for the German chemists Fritz Arndt (1885–1969) and Bernd Eistert (1902–1978), Arndt–Eistert synthesis is a popular method of producing β-amino acids from α-amino acids. Acid chlorides react with excess diazomethane to give diazoketones. In the presence of a nucleophile (water) and a metal catalyst (Ag2O), diazoketones will form the desired acid homologue.[4][5]
Scheme wrong, -HCl instead of -CH3Cl, otherwise number of carbons wrong
While the classic Arndt–Eistert synthesis uses thionyl chloride to prepare the acid chloride intermediate, alternative procedures can be used to effect this transformation. The diazoketone is traditionally generated using diazomethane, but other methods such as diazo-group transfer can also be applied.[6] Diazomethane is toxic and violently explosive, which has led to safer alternative procedures being developed,[7] such as the usage of ynolates (Kowalski ester homologation)[8] or diazo(trimethylsilyl)methane.[9][10]