Question

Reaction of methyl oxirane with grignard reagent followed by hydrolysis

Answer 1

Grignard reagents react with epoxides to form a new carbon-carbon bond with opening of the three-membered ring to give an alcohol after hydrolysis. There are two electrophilic carbon atoms, and the Grignard reagent attacks the less hindered carbon in an SN2 like reaction.

Answer 2

Answer:

Ethylmagnesium bromide is commercially available, usually as a solution in diethyl ether or tetrahydrofuran. It may be prepared in the normal manner of Grignard reagents — by reacting bromoethane with magnesium in diethyl ether: EtBr + Mg → EtMgBr.