Question

Reduction in pH of blood will :-
(1) reduce the rate of heart beat.
(2) reduce the blood supply to the brain.
(3) decrease the affinity of hemoglobin with oxygen.
(4) release bicarbonate ions by the liver
please explain

Answer 1

Hi,

3) decrease in the affinity of hemoglobin with oxygen.

This condition is known as acidemia and it causes shift of oxyhaemoglobin dissociation curve to the right.

Hope it helps ^_^

Answer 2

Reduction of pH of blood results will decrease the affinity of haemoglobin with oxygen.  

We can rule out options (1) and (2) as with decreased blood pH, the rate of heartbeat increases which results in the faster supply of blood to the brains. Option (4) can also be ruled out as low blood pH levels indicate low or no production of bicarbonate ions by the liver. Had it released bicarbonate ions then the pH of blood would not have gone low (acidic) in the first place.  

Option (3) is correct as affinity of haemoglobin to oxygen is directly proportional to its pH. So, reduction of blood pH will decrease the affinity of haemoglobin to oxygen.