Question

removal of which chain results in maturation of proinsulin to insulin? 1 Dchain, 2C chain 3 B chain, 4 A chain

Answer 1

Proinsulin is a single polypeptide chain composed of the B and A subunits of insulin joined by the C-peptide region. Proinsulin is converted to insulin during the maturation of secretory vesicles by the action of two proteases and conversion is inhibited by ionophores that disrupted intracellular H+ gradients.

Answer 2

Answer:

proinsulin has A B and C chains

while mature insulin has only A and B chains

so answer is C chain

Explanation: