Renin is an enzymatic hormone released by juxtaglomerular apparatus is in response to
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it helps to to maintain blood pressure, cell growth, and electrolytes balance. Ca2+ inhibit the enzyme and cAMP enhance the action of this enzyme
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Juxta glomerular apparatus(JGA) is a special sensitive region formed by cellular modifications in the distal convoluted tubule and the efferent arteriole at the location of their contact. A fall in glomerular filtration rate( the amount of the filtrate formed by the kidneys per minute ) can activate the JG cells to release renin which can stimulate the glomerular blood flow and thereby the GFR back to normal.
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