Question

Retrosynthesis of cyclohexenone

Answer 1

… The optically active 5-tert-butyldimethylsiloxy-2-cyclohexenone [(R)- and (S)-1], prepared in our laboratory, has proved to be an efficient chiral … Here we report the synthesis of (E)-4 from (S)-1 according to the retrosynthetic approach illustrated in Scheme 2