Question

retrovirus are dissolved before using to deliver desirable gene into animal cell give clear explanation ​

Answer 1

Retroviral vector-mediated gene transfer has been central to the development of gene therapy. ... The most important advantage that retroviral vectors offer is their ability to transform their single stranded RNA genome into a double stranded DNA molecule that stably integrates into the target cell genome.Retroviruses are among the most widely used viral vectors in gene therapy. They produce faithful transmission of the transgene into the transduced cell progeny by integrating their complementary DNA into the host genome during their life cycle (Miller, 1997; Verma and Somia, 1997).GM is a technology that involves inserting DNA into the genome of an organism. To produce a GM plant, new DNA is transferred into plant cells. Usually, the cells are then grown in tissue culture where they develop into plants. The seeds produced by these plants will inherit the new DNA.Adenoviruses are viruses that carry their genetic material in the form of double-stranded DNA. ... When these viruses infect a host cell, they introduce their DNA molecule into the host. The genetic material of the adenoviruses is not incorporated (transient) into the host cell's genetic material.Gene therapy is the introduction of genes into existing cells to prevent or cure a wide range of diseases. For example, suppose a brain tumor is forming by rapidly dividing cancer cells. ... The other target of some of the various retroviruses used include: bone marrow, skin, and liver cells.Retroviruses also have the enzyme reverse transcriptase, which allow it to copy RNA into DNA and use that DNA "copy" to infect human, or host, cells. When HIV infects a cell, it first attaches to and fuses with the host cell. ... The new copies of HIV then leave the host cell and move on to infect other cells.