Ria found that her younger brother getting vaccinated against polio disease. (2)
a) What does vaccine contain?
b) Write the principle of vaccination.
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a) POLIO SABIN (oral) vaccine is a magnesium chloride stabilised preparation of live attenuated polio viruses of the Sabin strains type 1 (LS-c, 2ab), type 2 (P712, Ch, 2ab) and type 3 (Leon 12ab). Each dose of OPV containsresidual amounts (less than 25 µg) of antibiotics including streptomycin and neomycin.
b) The action of oral polio vaccine (OPV) is two-pronged. OPV produces antibodies in the blood ('humoral' or serum immunity) to all three types of poliovirus, and in the event of infection, this protects the individual against polio paralysis by preventing the spread of poliovirus to the nervous system .
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