Biology, asked by Abhinv3115, 1 year ago

Role in tissue ph in the action of local anesthesia

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Answered by srividya99
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For the local anesthetic base to be stable in solution, it is formulated as a hydrochloride salt. ... The ph of all local anesthetics is >7.4 and therefore a greater proportion the molecules exists in the quaternary, water-soluble form when injected into tissue having normal pH of 7.4.
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