Role of actin filament in cell movement using lamellipodium
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Role of actin-filament disassembly in lamellipodium protrusion in motile cells revealed using the drug jasplakinolide. ... BACKGROUND: In motile cells, protrusion of the lamellipodium (a type of cell margin) requires assembly of actin monomers into actin filaments at the tip of the lamellipodium.
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Actin Filament in Cell Movement
Step by step explanation:
Actin cytoskeleton plays an essential role in the formation and the function of lamellipodia. The lamellipodial actin filaments are highly dynamic in nature.
The constant polymerization and the depolymerization of the actin filament produces the protrusive force that is required for the movement and the stretching of the lamellipodia.
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