Role of cdc cross match in kidney transplant patient review
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a more sensitive test would identify a positive crossmatch not identified by a less sensitive test and result in better outcomes. The benefit of the use of more sensitive crossmatch techniques was addressed by Salvalaggio et alin an analysis of OPTN registry data for transplants from 1987 through 2005. By multivariate Cox regression, compared with T AHG CDCXM– /B– crossmatch results, T–B– FCXM results were associated with a significantly lower incidence of acute rejection during the first one year after transplant (aOR=0.85, P<0.0001). Five-year graft survival after transplant with T–B– FCXM (82.6%) was modestly better than after T– AHG CDCXM/B– crossmatch (81.4%, P= 0.008) or T– AHG CDCXM (81.1%, P< 0.0001), but on adjusted analysis was significantly different only among recipients from deceased donors and patients aged > 60 years. An updated analysis of OPTN registry data from 1995–2009, performed by the authors for this article, showed similar results
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