Question

Role of glycogen phosphorylase in liver glycogen metabolism.

Answer 1

Answer:

The glycogen metabolism is controlled by the activity of glycogen synthase and glycogen phosphorylase. The major regulatory feature involved in the metabolism is phosphorylation, which inactivates glycogen synthase and activates glycogen phosphorylase.

Explanation:

Glycogen phosphorylase acts on the reaction at the initiation of glycogen degradation (Figure 4.5). Thereby, glucose can be obtained from glycogen. Glycogen phosphorylase causes phosphoroclastic cleavage into glycogen, and produces glycogen-1-phosphate. However, a non-reducing terminal is removed when cleaving glucose from glycogen.