role of lh and fsh in spermatogenesis
Answers
Answer:
Explanation:
the action of LH to stimulate spermatogenesis is complex involving several somatic cell types and a sequence of indirect signaling pathways. The foregoing notion is based on (1) the finding that murine germ cells from animals in which AR has been deleted are capable of spermatogenesis when transplanted into a recipient testis expressing AR the absence of compelling/consistent evidence for AR expression by germ cells.
FSH have shown that FSH increases germ cell numbers by several fold by increasing the complement of spermatogonia and spermatocytes but FSH was unable to generate spermatids in the absence of androgen consistent with studies of hypophysectomized rat in which FSH-stimulated post-meiotic germ cell development was inhibited in the absence of androgen signaling.
Answer:
In men, LH stimulates testosterone production from the interstitial cells of the testes (Leydig cells). FSH stimulates testicular growth and enhances the production of an androgen-binding protein by the Sertoli cells, which are a component of the testicular tubule necessary for sustaining the maturing sperm cell