role of melting point of drug in transdermal drug delivery
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The skin represents an extraordinary evolutionary feat. Not only does it physically encapsulate the organism and provide a multifunctional interface between us and our surroundings, but it is perpetually engaged in the assembly of a highly efficient homeostatic barrier to the outward loss of water 1. In so doing, it furnishes a membrane that is equally adept at limiting molecular transport both from and into the body. Overcoming this barrier function then, for the purpose of transdermal drug delivery, has been a necessarily …
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