Role of pleural fluid reactive protein in etiology and diagnosis of plural effusion
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Pleural effusion is one of the most common diagnoses made in the medicine wards.Pleural effusion is
classified in to exudative and transudative effusions based on Light’s criteria.In India infectious causes of
pleural effusion like Tuberculosis and parapneumonic effusions are the commonest causes of pleural
effusion.Tuberculosis is often diagnosed and treated empirically.The diagnosis of tuberculous effusion has
become simpler after the advent of pleural fluid ADA.Malignancy causes massive pleural effusion and the
diagnosis is made by the presence of malignant cells on cytology or on biopsy.Other causes of pleural effusion
include connective tissue disorders,pulmonary embolism,mesothelioma.C-Reactive protein is an acute phase
reactant that is elevated in blood and pleural fluid in many inflammatory conditions.This study is undertaken to
assess the usefulness of pleural fluid C-Reactive protein in the diagnosis of etiology of pleural effusion.
classified in to exudative and transudative effusions based on Light’s criteria.In India infectious causes of
pleural effusion like Tuberculosis and parapneumonic effusions are the commonest causes of pleural
effusion.Tuberculosis is often diagnosed and treated empirically.The diagnosis of tuberculous effusion has
become simpler after the advent of pleural fluid ADA.Malignancy causes massive pleural effusion and the
diagnosis is made by the presence of malignant cells on cytology or on biopsy.Other causes of pleural effusion
include connective tissue disorders,pulmonary embolism,mesothelioma.C-Reactive protein is an acute phase
reactant that is elevated in blood and pleural fluid in many inflammatory conditions.This study is undertaken to
assess the usefulness of pleural fluid C-Reactive protein in the diagnosis of etiology of pleural effusion.
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