Role of the pi3k/akt and mtor signaling pathways in acute myeloid leukemia
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Role of the PI3K/AKT and mTOR signaling pathways in acute myeloid leukemia. ... Constitutive PI3Kactivation is the result of autocrine IGF-1/IGF-1R signaling in 70% of acute myeloid leukemia samples but specific inhibition of this pathway does not induce apoptosis.
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