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In cell biology, contact inhibition refers to two different but closely related phenomena: contact inhibition of locomotion and contact inhibition of proliferation. CIL refers to the avoidance behavior exhibited by fibroblast-like cells when in contact with one another.
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Contact inhibition is a process of arresting cell growth when cells come in contact with each other.
As a result, normal cells stop proliferating when they form a monolayer in a culture dish. Contact inhibition is a powerful anticancer mechanism that is lost in cancer cells
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