Question

secondary amine and formic acid reaction​

Answer 1

The reaction required longer reaction times for electron poor aromatic amines and secondary amines but tolerated a variety of functional groups such as nitro, halogen, ester, ketone, and alkyl. The proposed reaction mechanism is similar to other acid catalyzed reactions of formic acid and amines.

Answer 2

Answer:

Eschweiler–Clarke reaction

Explanation:

the Eschweiler–Clarke methylation) is a chemical reaction whereby a secondary amine is methylated using excess formic acid and formaldehyde. Reductive amination reactions such as this one will not produce quaternary ammonium salts, but instead will stop at the tertiary amine stage