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Smaller cells have a better ratio which allows more molecules and ions to be manipulated across the cell membrane per unit of cytoplasmic volume. Cells are so small because they have to be ready to get the nutrients in and therefore the waste out quickly.
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Cells generally remain small in size and this is because of two reasons.
(i) Different regions of a cell can communicate with each other rapidly for the cell to function effectively.
(ii) Cells have a larger surface area / volume ratio for greater diffusion of substances in and out of the cell.
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