Question

Select the correct answer.
Tay-Sachs disease is caused by a mutation in the HEXA gene located on chromosome 15. Tay-Sachs follows an autosomal recessive pattern of inheritance. With the help of the diagram, identify which of the offspring will be an unaffected carrier.

a diagram showing the genes of parents who are carriers of Tay-Sachs disease

A.
A, B, and C
B.
B and C
C.
A and D
D. A
E. D

(TIP:if you dont know then dont answer )

Answer 1

Answer:

b. b and c

Explanation:

step by step

Answer 2

Answer:

B. B and C

Explanation:

Tay-Sachs disease is an autosomal recessive disease. It affects both males and females equally. The offspring with two recessive alleles will be affected by the disease.

One dominant allele in the genotype will make the offspring unaffected but he/she can transmit the disease to the next generation.

As given in the above picture, both mother and father are heterozygous with the genotype Rr and carriers of the disease.

1. Offspring A is rr, affected
2. Offspring B is Rr, unaffected, and carrier
3. Offspring C is Rr, unaffected, and carrier
4. Offspring D is RR, unaffected

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