Question

select the semi solid dosage form​

Answer 1

I hope it's helps you so,follow me mark as brainlist

Answer 2

Explanation:

Semisolid dosage forms are plastic in behavior hence they retain their shape on application of outside force. All semisolid dosage forms have a permanent three-dimensional structure that is responsible for their specific rheological character. Oil-in-water emulsions used in many pharmaceutical creams are not stabilized by the surfactant mechanical properties but rather stabilized by forming a gel network consisting of the structure-forming agents such as stearyl alcohol, cetyl alcohol, cetostearyl alcohol, etc. Cetostearyl alcohol is the combination of cetyl alcohol and stearyl alcohol. It is a crystalline bilayer/lamellae arrangement with attached surface molecules into the layer facing the hydrophilic portion of surfactants toward interlamellar space. This hydrophilic portion arrests water drainage from the interlamellar space, which in turn produces a gel that has the capacity to retain large volumes of water within the structure. In these emulsions (o/w) the oil phase is neither required for the delivery of water-soluble drugs nor for the gel formation but acts as a reservoir for the cetostearyl alcohol and is responsible for sensory characteristics of the formulation such as opacity. Cetostearyl alcohol and a hydrophilic surfactant are the primary structure-forming excipients used in semisolid dosage form, hence it is necessary to check for (1) the interactions and crystalline phase transition between them as it can change the semisolid nature of the dosage form (cream, gel, ointment, suppository), (2) physical properties, (3) drug release, and (4) pharmaceutical elegance (Narang and Boddu, 2015).