seribrospinal fluid function
Answers
Answer:
CSF assists the brain by providing protection, nourishment, and waste removal. CSF provides hydromechanical protection of the neuraxis through two mechanisms. First, CSF acts as a shock absorber, cushioning the brain against the skull. Second, CSF allows the brain and spinal cord to become buoyant, reducing the effective weight of the brain from its normal 1,500 grams to a much lesser 50 grams. The reduction in weight lessens the force applied to the brain parenchyma and cerebral vessels during mechanical injury. Another function of CSF is to maintain homeostasis of the interstitial fluid of the brain. A stable environment for brain parenchyma is imperative for maintaining normal neuronal function.
The major conduit of nutrient supply to the brain is the CP-CSF-ECSB nexus. Substrates needed by the brain are transported from the blood, through the CP, into the CSF, and then diffuse into the ECSB for transportation to their sites of action within the brain. CSF also assists in the removal of waste products of brain metabolism, such as products of peroxidation, glycosylated proteins, excess neurotransmitters, debris from the lining of the ventricles, bacteria, viruses, and otherwise unnecessary molecules. Accumulation of such unnecessary molecules, seen in aging and some neurodegenerative diseases, interferes with neuronal functioning of the brain. The great importance of CSF functioning is suggested by the disruption of cerebral physiology experienced with the disruption of the hydrodynamics or composition of CSF.
Answer:
CSF acts as a cushion or buffer, providing basic mechanical and immunological protection to the brain inside the skull. CSF also serves a vital function in the cerebral autoregulation of cerebral blood flow