Physics, asked by ayushiagrawal06, 1 year ago

short note on har gobind khurana

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Answered by chinmayajha
28
Har Gobind Khorana (9 January 1922 – 9 November 2011) was an Indian American biochemist. While on the faculty of the University of Wisconsin, he shared the 1968 Nobel Prize for Physiology or Medicine with Marshall W. Nirenberg and Robert W. Holley for research that showed the order of nucleotides in nucleic acids, which carry the genetic code of the cell and control the cell’s synthesis of proteins. Khorana and Nirenberg were also awarded the Louisa Gross Horwitz Prize from Columbia University in the same year...
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Answered by guycalledaji144
19
hi here your answer,
Dr. Hargobind Khorana was born in Raipur, Punjab (now in Pakistan) on January 2, 1922. He was the youngest of the five children in the family. He obtained his B.Sc. degree from the Punjab University as a student of D.A.V. College, Lahore. He got his M.Sc. degree in Chemistry in 1945 from the same University. For higher studies and education he went to Manchester University, Liverpool, England on a Government of India scholarship.

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There he studied under Professor A. Robertson and secured his first PhD, in 1948. He spent a year (1948-1949) as a post-doctoral fellow in Zurich and returned to India in 1949. He failed to get a suitable job in India so went back to England and worked with Nobel Laureate, Sir Alexander Todd at Cambridge University. Then he shifted to Canada in 1952. There he got married. In 1953 he was elected as the head of the Organic Group of Commonwealth Organization and worked on this post till 1960.

It was during this period that he developed deep and abiding interest in proteins and nucleic acids. In the same year he came to the University of Wisconsin and began his research in creation of artificial life. It was here that he succeeded in synthesizing DNA and RNA. In 1970 he became the Alfred Sloan Professor of biology and chemistry at Massachusetts Institute of Technology and continued his experiments and research.

Dr. Hargobind Khorana was awarded Nobel Prize for Medicine and Physiology in 1968 along with Marshall Nirenberg and Robert Holley for his interpretation of the genetic code and its function on protein synthesis. The gene involved was Escherichia coli, a bacteria that lives in intestines of human beings and animals.

He was the first to synthesize Oligonucleotides, that is, strings of nucleotides. These custom designed pieces of artificial genes are now commonly used in genetic labs for sequencing, cloning and engineering new animals and plants.
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