Question

Sickle cell anemia is due to gene modificatio related to amino acid of beta second chain

Answer 1

Sickle cell disease (SCD) is an autosomal recessive disorder in which a substitution of valine for glutamic acid in the β-chain hemoglobin molecule143 causes red blood cells to form sickle shapes and polymerize particularly when patients are exposed to hypoxemia or extremes of temperature or are dealing with infections.